Amino Pure Canada is a proudly Canadian source for premium peptides like BPC-157, TB-500, CJC-1295, NAD+ and GHK-Cu. HPLC-tested and ship fast from within Canada.
Semax
From
C$56.99
C$45.59
For Research Purpose Only
Scientific Overview and benefits:
Semax is a synthetic analog of ACTH (4-7) with modifications that enhance stability, bioavailability, and blood-brain barrier (BBB) permeability. The Pro-Gly-Pro (PGP) sequence increases lipophilicity, promoting passive diffusion and receptor-mediated transport. Acetylation protects against enzymatic degradation, extending half-life and efficacy.
Key Benefits
- Cognitive Enhancement – May improve memory, focus, and learning capacity through modulation of dopamine and brain-derived neurotrophic factor (BDNF).
- Neuroprotection – Potentially stabilizes neuronal function, reducing oxidative stress and preventing neural damage.
- Mood Regulation – Modulates dopaminergic and serotonergic pathways, possibly alleviating anxiety and stress-related symptoms.
- Pain and Stress Management – Inhibits enkephalin degradation, which may enhance natural pain relief and stress adaptation.
- Immune Support – Suggested to modulate gene expression, influencing chemokine and immunoglobulin levels for improved vascular and immune function.
Quantity
Molecular Makeup
Molecular Formula: C39H54N10O10S
Molecular Weight: 854.99 g/mol
Other Known Titles: ACTH (4-7)PGP, HY-P1146
Research Insights
Semax is a synthetic ACTH-derived peptide with neuroprotective, nootropic, and vascular benefits. It enhances serotonin metabolism, dopamine signaling, and blood-brain barrier permeability, promoting cognitive function and cardiovascular health.
Key Benefits
- Cognitive Enhancement – Boosts memory, focus, and learning capacity through increased serotonergic activity.
- Reduces Anxiety & Stress – Restores monoamine balance, potentially mitigating SSRI-induced anxiety in neonatal models.
- Supports Vascular Health – Protects cardiac function, preventing ventricular hypertrophy post-myocardial infarction.
- Aids Emotional Regulation – Normalizes stress responses, reducing anxiety caused by maternal deprivation.
- Promotes Neural Recovery – Enhances brain function restoration post-ischemic stroke, supporting neuroprotection.
Reference
Kost NV, Sokolov OIu, Gabaeva MV, Grivennikov IA, Andreeva LA, Miasoedov NF, Zozulia AA. Ingibiruiushchee deĭstvie semaksa i selanka na énkefalindegradiruiushchie fermenty syvorotki krovi cheloveka [Semax and selank inhibit the enkephalin-degrading enzymes from human serum]]. Bioorg Khim. 2001 May-Jun;27(3):180-3. Russian. doi: 10.1023/a:1011373002885. PMID: 11443939. https://pubmed.ncbi.nlm.nih.gov/11443939/
Nataliya Yu. Glazova, Daria M. Manchenko, Maria A. Volodina, Svetlana A. Merchieva, Ludmila A. Andreeva, Vladimir S. Kudrin, Nikolai F. Myasoedov, Natalia G. Levitskaya, Semax, synthetic ACTH(4–10) analogue, attenuates behavioural and neurochemical alterations following early-life fluvoxamine exposure in white rats, Neuropeptides, Volume 86, 2021, 102114, ISSN 0143-4179. https://doi.org/10.1016/j.npep.2020.102114
T. Kolomin et al., A New Generation of Drugs: Synthetic Peptides based on Natural Regulatory peptides. Neuroscience & Medicine, 2013, 223-252. Published Online December 2013. http://dx.doi.org/10.4236/nm.2013.44035
Reviews
Semax has been a game-changer for my mental clarity. I started using it during high-pressure work weeks and immediately noticed an improvement in focus, short-term memory, and stress control. It doesn’t feel stimulating—just sharp, calm energy that lasts all day. Easily one of the most effective nootropics I’ve tried.
I used Semax during my exam prep phase, and it helped tremendously. I retained information better, stayed focused for longer periods, and didn’t feel drained afterward. It’s now part of my rotation whenever I need to perform mentally at a high level. Highly recommended for students or anyone working long hours.
Semax m’a vraiment aidé à améliorer ma concentration et ma clarté mentale, surtout pendant les journées intenses. Effet rapide et sans effets secondaires. Service sérieux et livraison rapide.
clean packaging, effective delivery system, and consistent quality.
Very satisfied with the service and communication.
Highly recommended!
Semax nasal spray gives quick focus and mental clarity. Great for productivity without side effects.
Semax gives me that clean mental edge without the jitters. Super helpful for focus and motivation!
Arrived well-packaged and in perfect condition.
Excellent quality as always from Amino Pure Canada.
Semax helped improve concentration and reduced mental fatigue. Great for busy days
Clean, well-packaged, and effective. Improved focus and mental clarity within days.
Fast delivery, noticeable focus boost with Semax. Will order again!”