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Kisspeptin-10
From
C$81.99
C$65.59
Buy Kisspeptin-10 Peptide in Canada – Research-Grade KISS1-Derived Fragment
For Research Use Only - Kisspeptin-10 is a bioactive 10-amino-acid peptide derived from the KISS1 gene, which encodes a 145-amino-acid precursor protein. Through enzymatic cleavage, this precursor forms Kisspeptin-54, which is further processed into Kisspeptin-10 (residues 45–54) — a critical regulator of reproductive hormone signaling.
Scientific Overview
Reproductive Regulation: Kisspeptin-10 acts as a ligand for GPR54 (KISS1R), stimulating GnRH release from the hypothalamus and influencing gonadotropin secretion via the hypothalamic-pituitary-gonadal (HPG) axis.
Food Intake & Appetite: Research in animal models suggests Kisspeptin-10 may impact feeding behavior, reducing meal frequency and altering satiety signals. These effects appear to involve modulation of neuropeptide Y (NPY) and brain-derived neurotrophic factor (BDNF) expression in hypothalamic cells.
Neurochemical Pathways: Studies indicate Kisspeptin-10 may also influence serotonin and dopamine levels, providing further insight into its role in appetite regulation and central nervous system signaling.
At Amino Pure Canada, all peptides are HPLC-tested and supported by Certificates of Analysis (COAs). With fast, nationwide shipping, Kisspeptin-10 is supplied strictly as research-grade only, intended for laboratory and scientific studies.
Quantity
Molecular Makeup
Molecular Formula: C63H83N17O14
Molecular Weight: 1302.4 g/mol
Other Known Titles: Kisspeptin 45-54
Research Insights
Mechanism of Action
Kisspeptin-10, derived from the KISS1 gene, regulates gonadotropin-releasing hormone (GnRH), influencing reproductive function, hormone release, and neuroprotection. It interacts with GPR54 receptors, modulating various physiological processes.
Key Benefits
- Regulates Reproductive Hormones – Influences FSH and LH secretion, potentially aiding pubertal development and fertility.
- Enhances Emotional Response – Modulates limbic brain activity, increasing responsiveness to sexual and bonding stimuli.
- Supports Metabolic Function – Impacts food intake regulation, possibly reducing meal frequency while maintaining normal appetite control.
- Provides Neuroprotection – Potentially reduces amyloid-beta and alpha-synuclein toxicity, supporting cognitive health.
- Aids Hormonal Development – May help manage hypogonadotropic hypogonadism (HH) and polycystic ovarian syndrome (PCOS) by correcting hormonal imbalances.
Refrence
essager, S., Chatzidaki, E. E., Ma, D., Hendrick, A. G., Zahn, D., Dixon, J., Thresher, R. R., Malinge, I., Lomet, D., Carlton, M. B., Colledge, W. H., Caraty, A., & Aparicio, S. A. (2005). Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proceedings of the National Academy of Sciences of the United States of America, 102(5), 1761–1766. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC545088/
Mead, E. J., Maguire, J. J., Kuc, R. E., & Davenport, A. P. (2007). Kisspeptins: a multifunctional peptide system with a role in reproduction, cancer and the cardiovascular system. British journal of pharmacology, 151(8), 1143–1153. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189831/
omninos, A. N., Wall, M. B., Demetriou, L., Shah, A. J., Clarke, S. A., Narayanaswamy, S., Nesbitt, A., Izzi-Engbeaya, C., Prague, J. K., Abbara, A., Ratnasabapathy, R., Salem, V., Nijher, G. M., Jayasena, C. N., Tanner, M., Bassett, P., Mehta, A., Rabiner, E. A., Hönigsperger, C., Silva, M. R., Dhillo, W. S. (2017). Kisspeptin modulates sexual and emotional brain processing in humans. The Journal of clinical investigation, 127(2), 709–719. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5272173/
This peptide blend is provided for research and laboratory use only. Please review and adhere to our Terms and Conditions before ordering.
Why Amino Pure Canada for Peptides
At Amino Pure Canada, we supply HPLC-tested peptides in Canada — including BPC-157, TB-500, and NAD+. Backed by COAs and fast Canada-wide shipping, we’re a trusted national source for peptides Canada can rely on.
Reviews
Tried Kisspeptin from AminoPureCanada and I’m impressed with the quality. Packaging was secure and delivery was fast. Definitely ordering again!
Kisspeptin helped me feel more balanced emotionally and physically. My mood and energy are more stable, and I feel more in tune with my body. Subtle but powerful!
High-quality research product, exactly as described.
Delivery took a bit longer since I live in a rural area, but it was well worth the wait.
Thanks to Amino Pure Canada for the reliable service!
Kisspeptin has helped regulate my hormones naturally — I no longer need to rely on tablets.
Truly impressed by the results .Thank you for the excellent support!
product quality is excellent and well-packaged.
Only downside: shipping took a bit longer than expected.
Still very satisfied. Will order again!
J’utilise Kisspeptin-10 depuis quelques jours – super qualité.. Emballage propre, livraison rapide. Hâte de voir les effets à long terme !
Kisspeptin gave me a real boost — better mood, balanced hormones, and improved energy. Subtle but powerful. Love it!
Great price, good product