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DSIP
C$39.99
Buy DSIP Peptide in Canada – Research-Grade Delta Sleep-Inducing Peptide
For Research Use Only - Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring nonapeptide first identified in the central nervous system and studied for its potential role in sleep regulation and neuronal signaling. Research suggests DSIP may influence neurotransmitter balance by interacting with glutamatergic (NMDA), GABAergic, opioid, and adrenergic pathways.
Scientific Overview
NMDA & GABA Receptors: DSIP may reduce excitatory NMDA signaling while enhancing inhibitory GABA activity, contributing to sleep modulation.
Opioid Receptors: Possible indirect influence on opioid pathways, with studies suggesting a role in sleep cycles and withdrawal responses.
Adrenergic Pathways: DSIP has been linked to alpha-1 adrenergic receptors in the pineal gland, potentially modulating stress adaptation.
Research Highlights (Preclinical Studies)
Investigated for supporting sleep onset and sleep quality
Suggested involvement in stress tolerance and adaptation
Explored for potential analgesic (pain-modulating) properties
Studied in relation to withdrawal symptom mitigation
At Amino Pure Canada, we supply HPLC-tested peptides with Certificates of Analysis (COAs). With fast, nationwide shipping, DSIP is available strictly as research-grade only, intended for laboratory and scientific use.
Quantity
Molecular Makeup
Molecular Formula: C35H48N10O15
Molecular Weight: 848.82 g/mol
Other Known Titles: DSIP nonapeptide; emideltide
Research Insights
Delta Sleep-Inducing Peptide (DSIP) – Research Overview
Sleep Regulation
Preclinical studies suggest DSIP may enhance total sleep and slow-wave sleep (SWS), a deep sleep phase associated with restoration. Feline models exhibited increased sleep duration post-administration, with effects sustained for several hours. Clinical trials indicate DSIP may accelerate sleep onset and improve sleep efficiency.
Endocrine Modulation: DSIP is proposed to interact with hormones such as luteinizing hormone (LH) and growth hormone (GH), potentially contributing to sleep-related endocrine regulation. Murine studies observed elevated LH levels post-DSIP exposure, with GH secretion influenced by dopaminergic pathways.
Stress Response: Experiments on murine models suggest DSIP may modulate stress markers such as substance P, beta-endorphins, and corticosterone. DSIP exposure correlated with decreased corticosterone levels, potentially indicating stress-mitigating effects via the opioidergic system.
Longevity & Cellular Protection: Murine studies propose DSIP may reduce chromosomal aberrations in bone marrow and enhance lifespan. Additionally, DSIP may possess antioxidant properties, inhibiting lipid peroxidation and stimulating enzymatic defense mechanisms, potentially mitigating age-related oxidative stress.
Potential Benefits (Based on Preclinical Findings)
- Supports deep sleep & overall sleep efficiency
- May influence hormonal balance (LH & GH secretion)
- Possible stress-buffering effects via neurotransmitter interactions
- Suggested antioxidative & lifespan-extending properties
Reviews
Depuis que j’utilise DSIP, mes nuits sont beaucoup plus calmes et profondes. Je m’endors plus facilement et me réveille reposée. Merci pour ce produit de qualité et le service toujours au top. – Janine
Didn’t expect much, but DSIP really helped me unwind. My sleep feels deeper and more restful — it just works quietly in the background.
DSIP has made a real difference in my sleep. I fall asleep faster, stay asleep longer, and wake up feeling refreshed.
Deep, restful sleep every night. Wake up recharged. DSIP is a game-changer for anyone with sleep issues!
I added DSIP to my stack hoping for better rest, and it exceeded expectations. Highly recommended.
Falling asleep is easier and I wake up feeling refreshed. DSIP really improved my sleep quality!
DSIP helps me fall asleep faster and wake up refreshed. Works great!
Fell asleep faster and woke up refreshed. Very calming effect.
DSIP helps with deeper sleep. Very happy with the results!”