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5-Amino-1-MQ
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$80.99
Strictly for research purposes, not for human use.
5-Amino-1MQ (full name: 5-Amino-1-Methylquinolinium) is a synthetic small molecule compound developed by researchers at the University of Texas. Its primary function is to block — or "inhibit" — an enzyme in the body called NNMT (Nicotinamide N-Methyltransferase).
- NNMT is an enzyme that slows down how your cells burn energy and process fat. Think of it as a brake on your metabolism.
- In people who are overweight or aging, NNMT levels tend to be much higher — meaning the brake is always on.
- 5-Amino-1MQ works by blocking NNMT, which releases that brake — allowing cells to burn more energy, process fat more efficiently, and replenish a critical molecule called NAD+.
- NAD+ is essential for cell energy, DNA repair, and healthy aging. Lower NAD+ = slower metabolism, faster aging, weaker muscles.
Quantity
5-Amino-1-MQ to ship in 1 week
Why Is It Worth Researching?
-Amino-1MQ targets a biological pathway that no other well-known compound addresses directly. This makes it a genuinely novel research tool. Here is why the scientific community finds it compelling:
- Unique mechanism: It works through NNMT inhibition — a pathway completely separate from appetite suppressants, stimulants, or hormonal agents. This gives researchers a new angle to study metabolic disease.
- Works without changing food intake: In animal studies, fat loss occurred without any reduction in how much the subjects ate. This is significant — it suggests the mechanism is purely metabolic, not behavioral.
- Validated target: The NNMT enzyme as a therapeutic target has been validated in studies published in Nature — one of the most prestigious scientific journals in the world — by researchers at Harvard Medical School.
- Multiple research applications: The same compound shows potential relevance across obesity, diabetes, muscle aging, cancer biology, and cellular energy research — making it a versatile research tool.
- Oral bioavailability: Unlike many research peptides that require injection, 5-Amino-1MQ is water-soluble and can be administered orally in research settings, simplifying study design.
- No observed toxicity in preclinical models: At research doses, animal studies found no organ damage, behavioral changes, or cytotoxicity — making it a relatively clean compound to work with in controlled settings.
Main benefits
1. Fat Reduction & Metabolic Reprogramming
2. NAD+ Restoration
3. Muscle Aging & Sarcopenia
4.Gut Microbiome
5.Insulin Sensitivity
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